Can SSRIs Cause Permanent Brain Damage?

Do antidepressants permanently change your brain chemistry?

A single dose of SSRI antidepressants such as Fluoxetine, shown here, can change the brain’s functional connectivity within three hours, a new study found..

Do antidepressants affect memory?

Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory.

What is the mildest antidepressant?

These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are. SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro).

Can SSRIs damage your brain?

We need more research.” He notes, however, that SSRI’s have been in use for some 25 years and there is no evidence of brain damage or a negative impact on intellectual capacity.

Does your brain go back to normal after antidepressants?

The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.

Do antidepressants have long term side effects?

There is stronger evidence that the long-term use of one particular antidepressant, Paxil, does increase the risk of developing dementia. Still, these studies are all observational: They don’t prove that SSRIs cause the problems, only that their use is associated with them.

Do antidepressants shorten your life?

Though these pills may help in the short-term, a new study finds they could portend a serious health crisis later on in life, when taken long-term. Seems those who take selective serotonin reuptake inhibitors (SSRIs), the most popular kind, have a 33% higher mortality rate.

What is the hardest antidepressant to come off of?

Hardest-to-Stop Antidepressantscitalopram) (Celexa)escitalopram (Lexapro)paroxetine (Paxil)sertraline (Zoloft)

How long should you stay on antidepressants?

Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you’ve had three or more recurrences of depression, make that at least two years.

What are the long term effects of SSRIs?

The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials. During long-term SSRI therapy, the most troubling adverse effects are sexual dysfunction, weight gain, and sleep disturbance.

Do SSRIs permanently change your brain?

Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function.

How long does it take for serotonin levels to return to normal after SSRI?

In cases where serotonin syndrome is only present in a mild form, symptoms may be alleviated within 24 hours of discontinuing the medication causing the uptake in serotonin. However, some antidepressants can cause symptoms to last longer as serotonin levels may take weeks to return to normal.